A Clinical Study on the Efficacy of Vitamin B Supplements in the Treatment of Traumatic Ulceration

Xue Ding, Bao Zhou, Hao Zheng, Liuqun Sun and Yaping Zha

Background and Objective: Traumatic ulceration is a type of mouth ulcer caused by the accidental biting of the cheek or tongue, harsh brushing or poorly fitting dentures. Symptoms include pain, redness, swelling and soreness in the affected area. Vitamin B serves as a microelement necessary for its treatment. This study aims to evaluate the beneficial efficacy of vitamin B supplements in the treatment of traumatic ulceration. Materials and Methods: A total of 290 patients aged between 18-75 with traumatic ulceration were enrolled at Tongling People’s Hospital, Anhui Province, China which were randomly categorized into three groups’ viz. Vitamin B (N = 97) was given with oral vitamin B supplements and apply vitamin B12 solution topically on the oral mucosa, antibiotic group (N = 96) was given cefdinir capsule and the control (N = 97) was a placebo. The participants were evaluated for pain using a visual analog scale (VAS) and assessed for their efficacy. Results: The vitamin B group showed a significant reduction in ulcer size with 0.22±0.01 mm on day-8 and 100% healing rate by day-12. The vitamin B group also experienced a significant decrease in pain intensity score with 0.33±0.50 by day-8 and the pain intensity score was zero by day-12. The antibiotic group showed a limited and moderate improvement in pain intensity, indicating the superior effectiveness of vitamin B supplements in pain management. Whereas, the outcomes for the control group indicate a comparatively slower response in both ulcer size reduction and pain intensity compared to the vitamin B group and antibiotic group. Conclusion: The findings of this study conclude that vitamin B supplements is a viable and effective choice for managing pain and reducing ulcer size caused by traumatic ulceration.

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