Ying Yao, Zhihui Liu, Wengdong Qingn and Hao Wang
Background and Objective: Mixed haemorrhoids have interwoven varicose veins. This research assessed postoperative analgesia after stripping and ligating mixed haemorrhoids with ropivacaine and two sufentanil dosages. Materials and Methods: The 3 groups of 30 patients were randomly assigned: Group I received 0.75% ropivacaine (9 mg) with subarachnoid injection, whereas group II received the same dose plus 3 g sufentanil. Group III had 0.75% ropivacaine (9 mg) and 5 g sufentanil. All postoperative patients received patient-controlled intravenous analgesia (PCIA). Sufentanil 0.1 mg and tropisetron 10 mg were diluted to 100 mL in the analgesic pump with 0.9% sodium chloride. The analgesic pump, 1.5 mL PCIA single dose, 20 min locking time and 1 mL/hrs infusion continue for 24 hrs after surgery. General information, sensory block, motor block, anaesthesia impact, The VAS score at 2, 4, 6, 12 and 24 hrs after surgery, initial self-control, compressions, sufentanil dose and side effects were documented. Results: All three patient groups had identical sensory, motor and anaesthesia impact grading. Compared to group II, group III had lower VAS ratings. Both groups II and III showed substantial differences in initial self-control analgesia time, 24 hrs compressions and total sufentanil dose compared to group I. Initial self-control analgesia, 24 hrs compressions and total sufentanil dose differed significantly (p<0.05) between groups III and II. Respiratory depression, nausea, vomiting and urine retention were similar in all 3 groups. Conclusion: A subarachnoid block for a combination of hemorrhoid exfoliation and internal ligation anesthesia might extend postoperative patient-controlled analgesia and reduce intravenous sufentanil usage.
Ying Yao, Zhihui Liu, Wengdong Qingn and Hao Wang, 2024. Application Value of Ropivacaine Combined with Sufentanil Subarachnoid Block in Patients Undergoing External Stripping and Internal Ligation of Mixed Hemorrhoids. International Journal of Pharmacology, 20: 1404-1410.